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The Fogarty International Center of the U.S. National Institutes of Health (NIH) hosted the MISMS South Asia Influenza Meeting and Training Workshop at Dwarika's Hotel in Kathmandu, Nepal, August 9-13, 2011.
This was the tenth MISMS regional meeting focusing on the epidemiologic patterns associated with influenza virus circulation. Past meetings/workshops have been held at the NIH and in North America (Washington, DC), South America (Argentina), Asia (Vietnam and China), Europe (Portugal and Denmark), Africa (Senegal), and Oceania (Australia). These workshops are designed to help build analytical capacity for epidemiologic and molecular studies of influenza, to identify potential collaborators, and to disseminate new scientific findings that may serve to inform influenza control strategies.
The first two days of the meeting (August 9-10) featured scientific presentations focusing on the epidemiology, transmission dynamics, evolution, surveillance, and control of influenza viruses, while the last three days (August 11-13) consisted of a series of technical workshops during which MISMS staff assisted participants with the analysis of their own epidemiologic, vital statistic, and virologic data.
Thank you to Dwarika's Hotel and to all of our participants for making our South Asia Meeting and Workshop so successful. We look forward to continuing the collaborations and conversations that were created in Nepal. We very much hope you do the same!
Final Agenda Summary
Day
1- Tuesday, August 9: Scientific presentations
8:30am - 9:00 am Registration
9:00am - 10:10 pm Session I: Welcome and MISMS overview
9:00 - 9:30 am Mark Miller, Fogarty International Center, USA: Welcome and MISMS Overview.
9:30 - 9:50 am Wladimir Alonso, Fogarty International Center, USA and Origem Scientifica, Brazil: Influenza seasonality: Reconciling patterns across temperate and tropical populations.
9:50 - 10:10 am Cecile Viboud, Fogarty International Center, USA: Epidemiology and transmission dynamics of epidemic and pandemic influenza.
10:10-10:40 am Coffee Break
10:40 am - 12:00 pm Session II. Etiology of respiratory infections and clinical issues in South Asia
10:40 - 11:10 am Asad Ali, Aga Khan University, Pakistan: Role of influenza A in pediatric hospitalizations due to acute respiratory illnesses in Karachi, Pakistan.
11:10 - 11:30 am Ram Chandyo, IOM/MAL-ED, Nepal: Virus etiology in community acquired pneumonia in Bhaktapur, Nepal—cross-sectional and case-control study.
11:30 - 12:00 am Zeba Rasmussen, Fogarty International Center, USA: Prospective cohort study of pneumonia in Gilgit-Baltistan, Northern Pakistan.
12:00 pm-1:30 pm Lunch (provided)
1:30 - 2:20 pm Session III. Influenza virus evolution and relevance to public health
1:30 - 2:00 pm Martha Nelson, Fogarty International Center, USA: Spatial and evolutionary dynamics of influenza in humans and swine
2:00 - 2:20 pm Tan Yi, Fogarty International Center, USA: Evolutionary dynamics and epidemiology of influenza virus in Southern China.
2:20 - 3:20 pm Session IV. Influenza surveillance in Asia and the Pacific (Part 1)
2:20 - 2:40 pm Geeta Shakya, National Public Health Laboratory, Nepal: An experience with influenza surveillance in Nepal, 2010.
2:40 - 3:00 pm Sanjaya Shrestha, Walter Reed/AFRIMS Research Unit, Nepal: Sentinel human surveillance of influenza in Nepal.
3:00 - 3:20 pm Dibesh Karmacharya, Center for Molecular Dynamics, Nepal: Building molecular diagnostic capacity in the resource strapped countries for viral detection, surveillance, and monitoring- our experience in Nepal.
3:20 - 3:50 pm Coffee Break
3:50 - 5:10 pm Session IV. Influenza surveillance in Asia and the Pacific (Part 2)
3:50 - 4:10 pm Kedar Baral, Patan Academy of Health Sciences, Nepal: Epidemiological and virological surveillance of influenza like illness in Patan Academy of Health Sciences, Nepal.
4:10 - 4:30 pm Paul White, United Nations Food & Agriculture Organization, India: New approaches for old diseases: Sentinel and syndromic influenza surveillance in New Zealand.
4:30 – 5:10 pm Roundtable discussion: Influenza surveillance and research in South Asia.
Participants: Mark Steinhoff (Children’s Hospital of Cincinnati, USA), Zeba Rasmussen (FIC, USA), Asad Ali (AKU, Pakistan), Geeta Shakya (National Public Health Laboratory, Nepal), Nusrat Homaira (ICDDR,B, Bangladesh), Abdullah Mamun (ICDDR,B, Bangladesh), Mark Miller (FIC, USA)
Day
2- Wednesday, August 10: Scientific presentations
9:00 am - 10:30 am Session V. Disease burden and etiology II
9:00 - 9:20 am Siddhivinayak Hirve, KEM Hospital Research Center, Switzerland: Estimating age-specific global infection rates for the 2009 influenza pandemic influenza: a meta-analysis of H1N1pdm serological studies.
9:20 - 9:40 am Nusrat Homaira, ICDDR,B, Bangladesh: Incidence of influenza-associated mortality in Bangladesh: 2009.
9:40 - 10:10 am Rajesh Chudasama, MP Shah Medical College, India: Clinico-epidemiological features of the hospitalized patients with 2009 pandemic influenza A (H1N1) virus infection in Saurashtra region, India (September 2009 to February 2010).
10:10 - 10:30 am Dan Weinberger, Fogarty International Center, USA: Quantifying the impact of respiratory viruses on pneumococcal disease incidence.
10:30 - 11:00 am Coffee break
11:00 am - 12:40 pm Session VI. Issues in vaccination and health policy
11:00 - 11:20 am Mark Miller, Fogarty International Center, USA: Utilization of vaccines against influenza, considerations of epidemiology and resource limitations for epidemic and pandemic control.
11:20 - 11:40 am Mark Steinhoff, Cincinnati Children’s Hospital, USA: Influenza immunization in pregnancy and newborn outcomes.
11:40 am - 12:00 pm Abdullah Mamun, ICDDR,B, Bangladesh: Effectiveness of 2009 pandemic influenza A (H1N1) vaccine in Bangladesh, 2010: a program evaluation.
12:00 - 12:20 pm Mejbah U Bhuiyan, ICDDR,B, Bangladesh: Costs associated with hospitalizations with respiratory viral infections in Bangladesh.
12:20 - 12:40 pm Paul White, United Nations Food & Agriculture Organization, India: The science and art of coordinated national response to pandemics: Lessons learned during the influenza A (H1N1) 2009 outbreaks in New Zealand.
12:40 - 1:30 pm Lunch
1:30 - 3:00 pm Dataset presentations I. Disease burden and transmission dynamics.
Asad Ali, Aga Khan University, Pakistan: Surveillance of influenza A in children under two who are admitted to a public sector hospital with WHO-defined severe pneumonia.
Siddhivinayak Hirve, KEM Hospital Research Center, Switzerland: Estimating the burden of influenza in Pune, India using multiple datasets.
Nusrat Homaira, ICDDR,B, Bangladesh: Longitudinal assessment of risk factors for influenza and other respiratory virus specific pneumonia in children aged< 2 years.
Leilani Nillos, ARIVAC Project, Research Institute for Tropical Medicine, Philippines: Estimating influenza-associated excess mortality in the Philippines, 2004-2008.
3:00 - 3:30 pm Coffee break
3:30 - 5:00 pm Dataset presentations II: Avian Influenza.
Tika Ram, World Health Organization, Nepal: Avian Influenza Control Project – Surveillance in human and avian populations.
Ausraful Islam, ICDDR,B, Bangladesh: Role of wild waterfowl in avian influenza
Ireen Shanta, ICDDR,B, Bangladesh: National assessment of backyard poultry rearing practices in Bangladesh.
Muhammed Salah Uddin Khan, ICDDR,B, Bangladesh: Live bird market surveillance in Bangladesh, 2007 - 2011.
Najmul Haider, ICDDR,B, Bangladesh: Risk factors for H5N1 in backyard poultry flocks.
5:00 - 5:30 pm Mark Miller, FIC: Options for further collaborations and wrap-up.
Day 3- Thursday, August 11: Technical Workshops
9:00 - 10:30 am Wladimir Alonso and Dan Weinberger, FIC, USA: Practical in time-series and spatial analysis methodologies and tools; visualization of data.
10:30 - 11:00 am Coffee break
11:00 am - 12:00 pm Cecile Viboud, FIC, USA: Reproduction number estimation and disease modeling.
12:00 - 1:30 pm Lunch
1:30 - 2:30 pm Martha Nelson, FIC, USA: Phylogenetics 101.
2:30 - 3:00 pm Coffee break
3:00 - 5:00 pm Martha Nelson, FIC, USA: Introduction to the BEAST software package for Bayesian methods in phylogenetics.
Day 4- Friday, August 12: Technical Workshops
9:00 - 10:00 pm Yiming Bao, National Center for Biotechnology Information, National Library of Medicine, NIH, USA: The NCBI Influenza Virus Resource.
10:00 - 10:30 am Coffee break
10:30 am - 12:30 pm Hands-on tutorials, small group collaboration, one-on-one instruction.
12:30 - 1:30 pm Lunch
1:30 - 3:00 pm Hands-on tutorials, small group collaboration, one-on-one instruction.
3:00 - 3:30 pm Coffee break
3:30 - 5:00 pm Hands-on tutorials, small group collaboration, one-on-one instruction.
Day 5- Saturday, August 13: Technical Workshops
9:00 - 10:30 am Hands-on tutorials, small group collaboration, flexible schedule
10:30 - 11:00 am Coffee break
11:00 am - 12:30 pm Hands-on tutorials, small group collaboration, flexible schedule
12:30 - 1:30 pm Lunch
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Workshop |
Workshops
for epidemiologists and virologists led by the US National
Institutes of Health Fogarty International Center
Following
the meeting, a workshop describing the methodology to evaluate vital statistics,
virological, genomic and economic data to describe influenza disease burden and
inform policy will be held. It will consist of sessions designed for epidemiologists/virologists
and policy-makers who are interested in evaluating datasets that can be brought
to the meeting for further analysis. Workshops will concentrate on methodologies
to evaluate time-series data for regional or national analysis of influenza disease
burden, assessments of control, and evolution of influenza viruses. Participants
will have the opportunity to learn and apply tools to analyze national datasets
and formulate further collaborations on bi-national and multinational studies.
Please note that participation in the Thursday and Friday workshop sessions will
be limited. Participation will be based on submitted abstracts, which should include
a description of available datasets that participants may want to further analyze.
It
is highly recommended, but not required, that participants in the workshop bring:
- a laptop with some type of statistical software (i.e. SAS, STATA, or R)
- an influenza
dataset (vital statistics data, influenza isolate data, and vaccine coverage) preferred, but not required
Individuals
who attend the workshop will have the opportunity to learn about:
- time series
analysis
- spatial / temporal relationships
- influenza genomics tools
- data management issues
- SAS / Stata code
- strategies for evaluating vaccine benefits in a country using mortality data
- long-lasting research and surveillance collaborations
...and more!
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If you would like more information about this meeting, please contact us at ficmisms@mail.nih.gov.
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